Title: Senior Scientist – Cheminformatics & Computational Discovery
Location: Cambridge / Boston, MA (Hybrid/On-site)
Sector: Global Biopharmaceutical
Salary: $137,000 – $215,000 + Bonus + Comprehensive Benefits
About the Opportunity:
We are partnering with a world-class global pharmaceutical leader to identify an innovative Senior Scientist to join their Cheminformatics and Data Science division. This is a high-impact role aimed at championing a "prediction-priority" approach to drug discovery. You will be instrumental in bridging the gap between traditional medicinal chemistry and advanced computational modeling to accelerate life-changing therapeutic breakthroughs.
Key Responsibilities:
- Workflow Innovation: Design, automate, and implement sophisticated cheminformatics pipelines and data visualization platforms to empower discovery teams.
- Predictive Modeling: Develop and deploy machine learning models to optimize molecular design, drawing insights from massive chemical and biological datasets.
- Strategic Collaboration: Act as a key scientific partner to Global Medicinal Chemistry, DMPK, and AI/ML teams, identifying specific entry points in the DMTA (Design-Make-Test-Analyze) cycle where computational tools can reduce timelines.
- Cutting-Edge Research: Stay at the forefront of generative chemistry, large-scale chemical space exploration, and AI-driven discovery methods.
- DEL Expertise: Utilize computational methodologies to analyze DNA Encoded Library (DEL) data and apply Deep Learning techniques to enhance hit identification.
Candidate Profile:
- Education: PhD in Cheminformatics, Computational Chemistry, Computer Science, or a related quantitative field.
- Experience: A minimum of 2+ years of post-PhD experience within a biotech or pharmaceutical environment.
- Technical Skills: Expert-level proficiency in Python (specifically RDKit) or other languages like R or C++. Proven ability to build scalable, automated workflows.
- Domain Knowledge: Deep understanding of the drug discovery lifecycle and a track record of applying predictive tools to real-world design problems.
- Niche Skills (Preferred): Experience with Multi-task Deep Learning and DEL data analysis is highly desirable.
Why Join This Team?
My client offers a highly competitive compensation package, including robust short-term and long-term incentives. You will be joining an environment that values transparency and equity, providing top-tier medical/dental/vision coverage, generous 401(k) matching, and significant paid time off. This is a chance to work for a company that invests heavily in its talent and provides a clear roadmap for professional growth within the computational sciences.
Our client is an Equal Opportunity Employer dedicated to diversity and inclusion in the workplace.
