Scientist I – Discovery Research Immunology | Cambridge, MA

We are seeking a highly motivated Scientist I to join the Novel Modality Biology group within Discovery Research Immunology in Cambridge, MA. This is an exciting opportunity to contribute to cutting-edge early drug discovery research focused on immunological diseases in a highly collaborative and innovative environment.

Contract Duration: Through December 2026

Position Overview

The successful candidate will support the characterization of multi-specific biologics within discovery portfolio programs by designing, conducting, and analyzing in vitro assays to address key biological questions related to immunological diseases.

This role offers the opportunity to work at the intersection of basic research and early-stage therapeutic discovery while collaborating across multidisciplinary scientific teams.

Key Responsibilities

Design, execute, and analyze in vitro experiments using multi-specific biologics
Perform human immune cell culture and cell-based assay development
Isolate immune cells from human blood and tissue samples
Conduct and analyze multicolor flow cytometry experiments using platforms and software such as FlowJo
Perform ELISA/MSD assays to quantify pro-inflammatory proteins
Support biologic screening activities in human cell systems
Maintain detailed, accurate, and organized laboratory notebooks and experimental documentation
Present scientific findings and contribute to team discussions and research strategy
Collaborate effectively within a dynamic, multidisciplinary research environment

Required Qualifications

Bachelor’s or Master’s degree in Biological Sciences or related field with 2–3 years of relevant industry or laboratory experience
Strong background in:
In vitro cell culture
Human immunology and T cell biology
Multicolor flow cytometry
Primary human immune cell handling
Experience with flow cytometer operation and data analysis using FlowJo or similar software
Hands-on experience with:
ELISA/MSD assays
Tissue culture
Transfection
Cell line generation
SDS-PAGE
Immunoprecipitation
Western blotting
qPCR
Excellent organizational skills and meticulous record keeping
Strong written and verbal communication skills with the ability to work independently and collaboratively

Preferred Qualifications

Experience with biologic screening in human cell systems
Experience supporting early drug discovery or immunology-focused research programs

Why Join This Opportunity?

Work on innovative immunology and biologics discovery programs
Collaborate with leading scientists in a fast-paced research environment
Gain valuable experience at the intersection of translational science and early drug discovery
Contribute to impactful research targeting immunological diseases

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Scientist I – Discovery Research Immunology