At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we’re in. Are you?

About The Role

We’re looking for a Scientist on the Biologics Research team to help us expand what’s possible for patients with serious diseases. Reporting to the Senior Scientist, you’ll work within a multidisciplinary team of scientists focused on the design, engineering, and preclinical characterization of ground-breaking biotherapeutics. Specifically, you will help lead engineering and optimization campaigns for a diverse array of biomolecular scaffolds including binding and targeting moieties, signaling molecules, enzymes, and biological drug delivery platforms.

What You'll Do

In this role, you’ll be responsible for:

Driving biomolecular engineering efforts within Insmed research projects, including strategy and methods development
Construct recombinant systems encoding protein variants and combinatorial protein libraries
Conceptualize, construct, qualify, and implement high throughput screening platforms to enable candidate selection from large panels and/or combinatorial libraries of engineered protein variants
Conduct precision protein engineering to achieve specified design objectives, working both independently and in collaboration with computational biologists
Devise, optimize, and employ tailored protein expression and purification strategies for drug discovery programs
Develop, qualify, and deploy quantitative functional assays to characterize protein performance in vitro, and assess therapeutic candidate performance using in-vivo models
Contribute to collaborative prioritization and decision making on prospective discovery and development programs
Participating in cross-disciplinary mentoring and training within the RDL team
Present scientific results to the RDL team, Insmed research department, and external scientific community, as needed
Assist with coordination and day-to-day management of RDL site operations

Who You Are

You have a PhD or MS with 5+ years of experience in biochemistry, molecular biology, bioengineering, or related field.

You Also Have

Deep technical understanding of, and hands-on experience with, molecular biology, recombinant DNA technology, protein mutagenesis, and protein biochemistry
Recombinant protein expression and purification
Routine protein characterization methods including but not limited to spectroscopy, SDS-PAGE, western blot, ELISA
Protein-protein binding analysis
Experimental methods development, including experimental design, execution, and evaluation
PCR, molecular cloning, Cell culture (microbial and tissue culture), protein chromatography, BLI/SPR, ELISA, enzyme kinetics, electrophoresis, flow cytometry, spectroscopy, fluorimetry, etc.
Excellent communication skills (verbal and written)
High organization with a strong attention to detail and conciseness
Strong analytical and problem-solving skills
Broad knowledge of scientific principles and concepts

Nice To Have (but Not Required)

Experience with enzyme analysis a plus
Experience in high throughput functional screen development for protein libraries strongly preferred
Experience with lab automation is strongly preferred
Experience with next-generation sequencing strongly preferred

Where You’ll Work

This role is based in our New Jersey Research & Development Lab and requires full-time, in-person presence to support hands-on collaboration, access specialized equipment, and/or operational needs.

Travel Requirements

Minimal travel expected

Pay Range

$103,000.00-131,000.00 Annual

Life at Insmed

At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights Of Our U.S. Offerings Include

Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. 

Current Insmed Employees: Please apply via the Jobs Hub in Workday.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at TotalRewards@insmed.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.

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